Renal haemodynamics after chronic treatment with labetalol and propranolol.

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Effects of intravenous labetalol on blood pressure, angiotensin II and aldosterone in hypertension: comparison with propranolol.

1. Labetalol, a compound with both alpha- and beta-adrenoreceptor-blocking actions, was given intravenously (1-5-2-0 mg/kg) in twenty recumbent hypertensive patients. 2. There was a rapid reduction in systolic and diastolic pressures in all, maintained up to 24 h in some subjects. 3. Severe hypotension was not seen in recumbent subjects, but postural hypotension was common. 4. Labetalol caused ...

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ژورنال

عنوان ژورنال: British Journal of Clinical Pharmacology

سال: 1982

ISSN: 0306-5251

DOI: 10.1111/j.1365-2125.1982.tb01900.x